Alexander Hollaender was a leading researcher on the genetic effects of radiation. Born in Samter, Germany, in 1898 and arriving in the United States in 1921, Hollaender was educated at the University of Wisconsin, receiving his AB, MA, and Ph.D. there. He served on the faculty at the University of Tennessee and the University of Tennessee-Oak Ridge Graduate School of Biomedical Sciences. He was director of the division of biology at the Atomic Energy Commission's Oak Ridge National laboratory from 1946 until 1966. The 4 linear feet of the Alexander Hollaender Papers contain incoming and outgoing correspondence and reports relating to the genetic effects of radiation, specifically atomic radiation. Also included are documents of the International Conference on the Peaceful Uses of Atomic Energy; the NAS Committee on the Biological Effects of Atomic Energy, Genetics Panel; the United Nations Scientific Committee on Atomic Radiation; and the World Health Organization all of which Hollaender was closely involved with.

The collection includes three accessions: (1) a portion of Lewontin's correspondence files (mainly A-L) and copies of papers acquired in 1979; (2) a 2003 accession with files on various subjects and correspondence with about 30 colleagues, and (3) a substantial 2018 accession of about 60 linear feet that includes correspondence, manuscripts, and subject files. The topics discussed in the letters are numerous, including much on contemporary scientific controversies such as race, Darwin, evolution, intelligence, and biological determinism.

The James V. Neel Papers document nearly every phase of the career of one of the founders of human population genetics in the United States. Neel was particularly thorough and organized, and retained virtually all of his significant scientific correspondence, committee reports, minutes of meetings, and drafts of manuscripts. The collection also includes data collected during Neel's work among the Xavante, Yanomanö and other indigenous populations. In a career that spanned the period from the late work of Thomas Hunt Morgan and Charles B. Davenport to the contemporary world of molecular genetics and nucleic acids, Neel knew, worked with, and corresponded with many of the most influential 20th century practitioners of genetics. The collection begins in earnest in 1943, after Neel had decided to focus on human genetics. Neel's work with Drosophila and none of his Drosophila manuscripts are found in the collection.